Chagas disease is an emerging infection in Italy as the consequence of the huge immigration from Latin American countries observed during the last ten-fifteen years. However, the interest of Italian researchers on Chagas disease dates back to the '80-90s of the last century with studies conducted in collaboration with Brazilian and Argentinian colleagues by Italian cardiologists and pathologists. Moreover, the first demonstration of the existence in the pre-Columbian America of Chagas disease in a Peruvian mummy was made by a group of Italian paleopathologists. Seroprevalence studies performed between 2010-2014 in Negrar (Verona), Bergamo, Milan, Florence and Rome shows T. cruzi infection ranging from 3.9% to 17.1% with people coming from Bolivia as the most affected. As observed in Latin America about 30% of screened subjects in Italy are affected by cardiac or digestive forms of Chagas disease. More than 20% of subjects treated with benznidazole discontinued it permanently due to adverse events.
A review of Chagas disease in Italy and the study's contribution of Italian researchers / S. Antinori, A. Ridolfo, A. Giacomelli, C.M. Bonazzetti, M. Corbellino, M. Galli. - In: PANMINERVA MEDICA. - ISSN 0031-0808. - (2019). [Epub ahead of print] [10.23736/S0031-0808.19.03723-6]
A review of Chagas disease in Italy and the study's contribution of Italian researchers
S. Antinori
Primo
;A. Giacomelli;C.M. Bonazzetti;M. Galli
2019
Abstract
Chagas disease is an emerging infection in Italy as the consequence of the huge immigration from Latin American countries observed during the last ten-fifteen years. However, the interest of Italian researchers on Chagas disease dates back to the '80-90s of the last century with studies conducted in collaboration with Brazilian and Argentinian colleagues by Italian cardiologists and pathologists. Moreover, the first demonstration of the existence in the pre-Columbian America of Chagas disease in a Peruvian mummy was made by a group of Italian paleopathologists. Seroprevalence studies performed between 2010-2014 in Negrar (Verona), Bergamo, Milan, Florence and Rome shows T. cruzi infection ranging from 3.9% to 17.1% with people coming from Bolivia as the most affected. As observed in Latin America about 30% of screened subjects in Italy are affected by cardiac or digestive forms of Chagas disease. More than 20% of subjects treated with benznidazole discontinued it permanently due to adverse events.File | Dimensione | Formato | |
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