3D microscaffoldsare becoming more and more relevant in regenerative medicine, as they lead to the creation of a structure similar to a physiologicalniche. An example is the nano-engineered Nichoid, a 3D structure in which the cells are able to proliferate. In this work,we investigated the proliferation and stemness properties of Er-NPCswhen grown inside the Nichoid, and their potential therapeutic application in the treatment of Parkinson’s Disease.

3D microscaffolds are becoming more and more relevant in regenerative medicine, as they lead to the creation of a structure similar to a physiological niche. An example is the nano-engineered Nichoid, a 3D structure in which the cells are able to proliferate. In this work, we investigated the proliferation and stemness properties of Er-NPCs when grown inside the Nichoid, and their potential therapeutic application in the treatment of Parkinson’s Disease.

Therapeutic effect of neural progenitor cells expanded in the 3D nano-engineered Nichoid substrate in a Parkinson’s disease preclinical model / S. Carelli, T. Giallongo, F. Rey, B. Barzaghini, G. Al Haj, T. Zandrini, G. Cerullo, R. Osellame, A.M. Di Giulio, M.T. Raimondi. ((Intervento presentato al convegno ESB-ITA Meeting 2019 tenutosi a Bologna nel 2019.

Therapeutic effect of neural progenitor cells expanded in the 3D nano-engineered Nichoid substrate in a Parkinson’s disease preclinical model

S. Carelli;T. Giallongo;F. Rey;G. Al Haj;A. M. Di Giulio;
2019-10-01

Abstract

3D microscaffoldsare becoming more and more relevant in regenerative medicine, as they lead to the creation of a structure similar to a physiologicalniche. An example is the nano-engineered Nichoid, a 3D structure in which the cells are able to proliferate. In this work,we investigated the proliferation and stemness properties of Er-NPCswhen grown inside the Nichoid, and their potential therapeutic application in the treatment of Parkinson’s Disease.
3D microscaffolds are becoming more and more relevant in regenerative medicine, as they lead to the creation of a structure similar to a physiological niche. An example is the nano-engineered Nichoid, a 3D structure in which the cells are able to proliferate. In this work, we investigated the proliferation and stemness properties of Er-NPCs when grown inside the Nichoid, and their potential therapeutic application in the treatment of Parkinson’s Disease.
Parkinson’s disease; Nichoid; biomechanical manipulation; regenerative medicine;
Settore BIO/13 - Biologia Applicata
http://www.esb-ita.it/wp-content/uploads/2019/09/ESB-ITA-2019-mai_mai_dire_final_program.pdf
Therapeutic effect of neural progenitor cells expanded in the 3D nano-engineered Nichoid substrate in a Parkinson’s disease preclinical model / S. Carelli, T. Giallongo, F. Rey, B. Barzaghini, G. Al Haj, T. Zandrini, G. Cerullo, R. Osellame, A.M. Di Giulio, M.T. Raimondi. ((Intervento presentato al convegno ESB-ITA Meeting 2019 tenutosi a Bologna nel 2019.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/675693
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