Background. To assess the potential usefulness of 18F-FDG/PET and spiral-CT images concurrent assessment and coregistration in staging mediastinal lymph node involvement in patients with non small cell lung cancer. Methods. 28 patients waiting to undergo surgical treatment underwent spiral-CT and PET examinations on the same day. The results of the two studies were interpreted separately, together (CT AND PET) and following their fusion in a single image (CT+PET). Results of spiral-CT, PET, CT AND PET and CT+PET were assessed with respect to the histological diagnosis. Results. A correct assessment of mediastinal lymph nodes was achieved by spiral-CT in 21 of the 28 patients, in 22 of the 28 patients by PET, in 24 patients by CT AND PET and in 25 patients by CT+PET. Conclusions. CT+PET is more accurate than spiral-CT and PET alone in staging mediastinal lymph node involvement in lung cancer patients, with possible implications for their prognosis and therapy.
FDG/PET and spiral CT image fusion for mediastinal lymph node assessment of non-small cell lung cancer patients / P. Magnani, A. Carretta, G. Rizzo, F. Fazio, A. Vanzulli, G. Lucignani, P. Zannini, C. Messa, C. Landoni, M. Gilardi, A. Del Maschio. - In: MINERVA PNEUMOLOGICA. - ISSN 0026-4954. - 39:2(2000), pp. 69-77.
FDG/PET and spiral CT image fusion for mediastinal lymph node assessment of non-small cell lung cancer patients
A. Vanzulli;G. Lucignani;
2000
Abstract
Background. To assess the potential usefulness of 18F-FDG/PET and spiral-CT images concurrent assessment and coregistration in staging mediastinal lymph node involvement in patients with non small cell lung cancer. Methods. 28 patients waiting to undergo surgical treatment underwent spiral-CT and PET examinations on the same day. The results of the two studies were interpreted separately, together (CT AND PET) and following their fusion in a single image (CT+PET). Results of spiral-CT, PET, CT AND PET and CT+PET were assessed with respect to the histological diagnosis. Results. A correct assessment of mediastinal lymph nodes was achieved by spiral-CT in 21 of the 28 patients, in 22 of the 28 patients by PET, in 24 patients by CT AND PET and in 25 patients by CT+PET. Conclusions. CT+PET is more accurate than spiral-CT and PET alone in staging mediastinal lymph node involvement in lung cancer patients, with possible implications for their prognosis and therapy.
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