The highest rate of complications characterizing the adult living donor liver transplantation (ALDLT) are due to biliary problems with a reported negative incidence of 22-64%. We performed 23 ALDLT grafting segments V-VIII without the middle hepatic vein from March 2001 to September 2005. Biliary anatomy was investigated using intraoperative cholangiography alone in the first five cases and magnetic resonance cholangiography in the remaining 18 cases. In 13 cases we found a single right biliary duct (56.5%) and in 10 we found multiple biliary ducts (43.7%). We performed single biliary anastomosis in 17 cases (73.91%) and double anastomosis in the remaining six (26%) cases. With a mean follow up of 644 days (8-1598 days), patient and graft survivals are 86.95% and 78.26%, respectively. The following biliary complications were observed: biliary leak from the cutting surface: three, anastomotic leak: two, late anastomotic strictures: five, early kinking of the choledochus: one. These 11 biliary complications (47.82%) occurred in eight patients (34.78%). Three of these patients developed two consecutive and different biliary complications. Biliary complications affected our series of ALDLT with a high percentage, but none of the grafts transplanted was lost because of biliary problems. Multiple biliary reconstructions are strongly related with a high risk of complication.
Biliary complications after living donor adult liver transplantation / A. Giacomoni, A. Lauterio, A.O. Slim, A. Vanzulli, A. Calcagno, I. Mangoni, L.S. Belli, A. De Gasperi, L. De Carlis. - In: TRANSPLANT INTERNATIONAL. - ISSN 0934-0874. - 19:6(2006), pp. 466-473. ((Intervento presentato al 12. convegno Congress of the European-Society-for-Organ-Transplantation tenutosi a Geneva nel 2005.
|Titolo:||Biliary complications after living donor adult liver transplantation|
|Parole Chiave:||biliary anatomy assessment; biliary complications; liver transplantation; living donor liver transplantation; magnetic resonance cholangiography; split liver|
|Settore Scientifico Disciplinare:||Settore MED/13 - Endocrinologia|
|Data di pubblicazione:||2006|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1111/j.1432-2277.2006.00274.x|
|Appare nelle tipologie:||01 - Articolo su periodico|