Objective. To identify the clinical features that can help to distinguish between psoriatic arthritis (PsA) and fibromyalgia (FM). Methods. Our cross-sectional study was carried out in 10 Italian rheumatology centers between January and September 2009, and enrolled all consecutive patients with PsA and FM who agreed to participate. Standard clinical and laboratory data for PsA and FM were collected from all patients. Records were made of somatic symptoms, response to nonsteroidal antiinflammatory drugs (NSAID), self-evaluated pain, general health, disability, and responses to the Fibromyalgia Impact Questionnaire. Data were statistically analyzed by univariate and multivariate analyses, and receiver- operating characteristic curves. The analysis concentrated on the clinical features shared by the 2 conditions. Results. Two hundred sixty-six patients with PsA (mean age 51.7 yrs; disease duration 10.2 yrs) and 120 patients with FM (mean age 50.2 yrs; disease duration 5.6 yrs) were evaluated. Univariate analysis showed that patients with FM had higher mean tender point and enthesitis scores, more somatic symptoms, and responded less to NSAID. Multivariate analysis showed that the presence of ≥ 6 FM-associated symptoms and ≥ 8 tender points was the best predictor of FM. Conclusion. The shared clinical features of PsA and FM that had the greatest discriminating power for FM were the number of FM-associated symptoms and tender point count.

Identification of the clinical features distinguishing psoriatic arthritis and fibromyalgia / A. Marchesoni, F. Atzeni, A. Spadaro, E. Lubrano, G. Provenzano, A. Cauli, I. Olivieri, D. Melchiorre, C. Salvarani, R. Scarpa, P. Sarzi-Puttini, M. Montepaone, G. Porru, S. D'Angelo, M. Catanoso, L. Costa, M. Manara, V. Varisco, L. Rotunno, O. De Lucia, G. De Marco. - In: THE JOURNAL OF RHEUMATOLOGY. - ISSN 0315-162X. - 39:4(2012 Apr), pp. 849-855. [10.3899/jrheum.110893]

Identification of the clinical features distinguishing psoriatic arthritis and fibromyalgia

P. Sarzi-Puttini;M. Manara;V. Varisco;O. De Lucia;G. De Marco
2012

Abstract

Objective. To identify the clinical features that can help to distinguish between psoriatic arthritis (PsA) and fibromyalgia (FM). Methods. Our cross-sectional study was carried out in 10 Italian rheumatology centers between January and September 2009, and enrolled all consecutive patients with PsA and FM who agreed to participate. Standard clinical and laboratory data for PsA and FM were collected from all patients. Records were made of somatic symptoms, response to nonsteroidal antiinflammatory drugs (NSAID), self-evaluated pain, general health, disability, and responses to the Fibromyalgia Impact Questionnaire. Data were statistically analyzed by univariate and multivariate analyses, and receiver- operating characteristic curves. The analysis concentrated on the clinical features shared by the 2 conditions. Results. Two hundred sixty-six patients with PsA (mean age 51.7 yrs; disease duration 10.2 yrs) and 120 patients with FM (mean age 50.2 yrs; disease duration 5.6 yrs) were evaluated. Univariate analysis showed that patients with FM had higher mean tender point and enthesitis scores, more somatic symptoms, and responded less to NSAID. Multivariate analysis showed that the presence of ≥ 6 FM-associated symptoms and ≥ 8 tender points was the best predictor of FM. Conclusion. The shared clinical features of PsA and FM that had the greatest discriminating power for FM were the number of FM-associated symptoms and tender point count.
Enthesitis; Fibromyalgia; Pain; Psoriatic arthritis; Adult; Arthritis, Psoriatic; Cross-Sectional Studies; Diagnosis, Differential; Female; Fibromyalgia; Humans; Male; Middle Aged
Settore MED/16 - Reumatologia
apr-2012
Article (author)
File in questo prodotto:
File Dimensione Formato  
849.full.pdf

accesso riservato

Tipologia: Publisher's version/PDF
Dimensione 188.02 kB
Formato Adobe PDF
188.02 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/667541
Citazioni
  • ???jsp.display-item.citation.pmc??? 23
  • Scopus 94
  • ???jsp.display-item.citation.isi??? 86
social impact