For many years, melatonin has been known to interact with circadian rhythms. New evidence indicates that melatonin acts as a free radical scavenger and antioxidant. Moreover, melatonin prevents apoptosis in different types of cells, because it induces mRNA levels of several antioxidant enzymes. It is evident that melatonin is involved in the cellular bioenergetic system as a mechanism that counteracts the progression of Alzheimer''s disease.
Melatonin : circadian rhythm regulator, chronobiotic, antioxidant and beyond / B. Berra, A.M. Rizzo. - In: CLINICS IN DERMATOLOGY. - ISSN 0738-081X. - 27:2(2009), pp. 202-209.
Melatonin : circadian rhythm regulator, chronobiotic, antioxidant and beyond
B. BerraPrimo
;A.M. RizzoUltimo
2009
Abstract
For many years, melatonin has been known to interact with circadian rhythms. New evidence indicates that melatonin acts as a free radical scavenger and antioxidant. Moreover, melatonin prevents apoptosis in different types of cells, because it induces mRNA levels of several antioxidant enzymes. It is evident that melatonin is involved in the cellular bioenergetic system as a mechanism that counteracts the progression of Alzheimer''s disease.
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