In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.
Antiulcer agents : from plant extracts to phytochemicals in healing promotion / M. Sharifi-Rad, P.V.T. Fokou, F. Sharopov, M. Martorell, A.O. Ademiluyi, J. Rajkovic, B. Salehi, N. Martins, M. Iriti, J. Sharifi-Rad. - In: MOLECULES. - ISSN 1420-3049. - 23:7(2018), pp. 1751.1-1751.37. [10.3390/molecules23071751]
Antiulcer agents : from plant extracts to phytochemicals in healing promotion
M. Iriti;
2018
Abstract
In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to Helicobacter pylori activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.
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