In human medicine the concentration of serum endothelin-1 (ET-1)increases in hypertension and CKD. Also urinary ET-1 correlates withthe severity of renal disease and the magnitude of proteinuria. In dogs,increased concentration of ET-1, evaluated indirectly by the precursorBig Endothelin-1 (big-ET1), seems to be associated with the severityof CKD and hypertension.The aim of this study was to gain information about serum and urinarylevels of big-ET1 in cats with CKD, with and without hypertensionand proteinuria.

Big endothelin-1 in cats with CKD : preliminary evaluation / P. Scarpa, C. Piazza, B. Ruggerone, S. Paltrinieri, M. Giraldi. - In: JOURNAL OF VETERINARY INTERNAL MEDICINE. - ISSN 0891-6640. - 33:2(2019 Mar), pp. 1095-1095. ((Intervento presentato al convegno ECVIM-CA Congress tenutosi a Rotterdam (The Netherlands) nel 2018.

Big endothelin-1 in cats with CKD : preliminary evaluation

P. Scarpa;B. Ruggerone;S. Paltrinieri;M. Giraldi
2019-03

Abstract

In human medicine the concentration of serum endothelin-1 (ET-1)increases in hypertension and CKD. Also urinary ET-1 correlates withthe severity of renal disease and the magnitude of proteinuria. In dogs,increased concentration of ET-1, evaluated indirectly by the precursorBig Endothelin-1 (big-ET1), seems to be associated with the severityof CKD and hypertension.The aim of this study was to gain information about serum and urinarylevels of big-ET1 in cats with CKD, with and without hypertensionand proteinuria.
Settore VET/08 - Clinica Medica Veterinaria
Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria
Biomarkers of Proteinura and Hypertension as risk factors for development and worsening of feline CKD
https://onlinelibrary.wiley.com/doi/10.1111/jvim.15372
Article (author)
File in questo prodotto:
File Dimensione Formato  
2019-Journal_of_Veterinary_Internal_Medicine-2.pdf

accesso aperto

Tipologia: Publisher's version/PDF
Dimensione 67.39 kB
Formato Adobe PDF
67.39 kB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/658065
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact