Objective: The purpose of the paper is to examine the current state of the art about epidemiology, diagnosis, and treatment of this infection. Methods: A review of the literature was performed through a PubMed search of original articles, case reports, and reviews using the key words “brain abscess,” “cerebral abscess,” “brain infection,” “intracranial suppuration,” “otogenic brain abscess,” “otitis complications,” and “sinusitis complications.” Results: Pediatric brain abscess is a rare but serious infection, often involving patients with specific risk factors and burdened by a high risk of morbidity and mortality. Brain abscess incidence and mortality decreased over the years, thanks to improved antibiotic therapy, new neurosurgical techniques, and the wide spread of vaccinations. There are no guidelines for the adequate diagnostic-therapeutic pathway in the management of brain abscesses; therefore, conflicting data emerge from the literature. In the future, multicentric prospective studies should be performed in order to obtain stronger evidences about brain abscesses management. Over the next few years, changes in epidemiology could be observed because of risk factors changes.
Brain abscess in pediatric age: a review / C. Mameli, T. Genoni, C. Madia, C. Doneda, F. Penagini, G. Zuccotti. - In: CHILDS NERVOUS SYSTEM. - ISSN 0256-7040. - 35:7(2019 Jul), pp. 1117-1128.
|Titolo:||Brain abscess in pediatric age: a review|
MAMELI, CHIARA (Primo) (Corresponding)
GENONI, TERESA (Secondo)
ZUCCOTTI, GIAN VINCENZO (Ultimo)
|Parole Chiave:||Brain abscess; Central nervous system infections; Children; Intracranial infection|
|Settore Scientifico Disciplinare:||Settore MED/38 - Pediatria Generale e Specialistica|
|Data di pubblicazione:||lug-2019|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1007/s00381-019-04182-4|
|Appare nelle tipologie:||01 - Articolo su periodico|
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