One of the most important complications of portal hypertension, in the setting of liver cirrhosis or of non-cirrhotic portal hypertension, is upper gastrointestinal bleeding from ruptured gastroesophageal varices and portal hypertensive gastropathy. The management of the acute variceal bleeding is a multidisciplinary process that includes the initial assessment of the patient, effective resuscitation, timely diagnosis, control of bleeding and prevention of early rebleeding and complications such as infection, hepatorenal syndrome, or hepatic encephalopathy. Antibiotic prophylaxis, conservative targets for blood transfusions and combination therapy with vasoactive drugs and endoscopic treatments are the first-line measures in the management of acute variceal bleeding; transjugular intrahepatic portosystemic shunts should be proposed early to high-risk patients or as a rescue therapy for those who fail first-line treatment.
Endoscopic management of variceal haemorrhage / A. Dell'Era, F. Iannuzzi, R. de Franchis. - In: JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY RESEARCH. - ISSN 2224-3992. - 4:3(2015), pp. 1507-1514.
Titolo: | Endoscopic management of variceal haemorrhage |
Autori: | |
Parole Chiave: | Acute variceal bleeding; Antibiotic prophylaxis; Ectopic varices; Endoscopic sclerotherapy; Endoscopic variceal ligation; Esophageal varices; Gastric varices; TIPS; Vasoactive drugs; Hepatology; Gastroenterology |
Settore Scientifico Disciplinare: | Settore MED/12 - Gastroenterologia |
Data di pubblicazione: | 2015 |
Rivista: | |
Tipologia: | Article (author) |
Digital Object Identifier (DOI): | http://dx.doi.org/10.6051/j.issn.2224-3992.2015.03.495-4 |
Appare nelle tipologie: | 01 - Articolo su periodico |
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