IRIS Institutional Research Information System - AIR Archivio Istituzionale della Ricerca

IRIS è il sistema di gestione integrata dei dati della ricerca (persone, progetti, pubblicazioni, attività) adottato dall'Università degli Studi di Milano.

AIR nasce in UNIMI nel 2006 con lo scopo di raccogliere, documentare e conservare le informazioni sulla produzione scientifica dell'Università degli Studi di Milano e costituisce di fatto l'Anagrafe della ricerca dell'Ateneo.

Most patients with squamous cell carcinomas of the head and neck (SCCHN) present with incurable or recurrent disease, and many who are cured acquire unacceptable functional and cosmetic deficits as a consequence of conventional therapy [1,2]. Effective cytotoxic treatment regimens may eventually cure patients in advanced stages as well as prevent recurrences and reduce the undesirable consequences of conventional therapy in patients with earlier stages [3–5]. Overall and complete response (CR) rates in the range of 80–90% and 35–54% respectively, have been reported in advanced tumors [1]. CR rates above 80% have been described recently in pilot trials using intensive chemotherapy or concurrent chemo-radiotherapy [6–7]. Patients achieving clinical CR demonstrate survival advantages [1–5] which are particularly evident when therapy results in the eradication of microscopic disease [8]. Nevertheless, following initial treatment, 50% of the patients achieve less than a CR, and 50% of the CRs are associated with residual microscopic disease.

Methodology and Clinical Applications of Cellular DNA Content Parameters Determined by Flow Cytometry in Squamous Celi Cancers of the Head and Neck / J.F. Ensley, L. Maciorowski, H. Pietraszkiewicz, F. de Braud, W. and Sakr (CANCER TREATMENT AND RESEARCH). - In: Carcinomas of Head and Neck : Evaluation and managment / [a cura di] C. Jacobs. - Boston : Kluvert Academic Publishers,, 1990. - ISBN 9781461288060. - pp. 225-242

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