We report the first case of sclerosing angiomatoid nodular transformation (SANT) of the spleen diagnosed during pregnancy, discussing differential diagnosis, immunohistochemical profile and treatment. A G2P1 37-year-old woman presented during the 19th week of gestation because of pruritus at lower limbs. To exclude cholestasis, an abdominal ultrasound and whole body magnetic resonance were performed and a single solid lesion with intrinsic vascularization was identified. Therefore, at 22 weeks gestation, after normal fetal assessment, the patient was referred for a splenectomy. No further treatment was suggested and the patient gave birth at 42 weeks gestation with a spontaneous delivery. Distinguishing SANT from other vascular neoplasms of the spleen during pregnancy is a difficult task. Surgical excision should be performed to exclude malignancy and to resolve symptoms, if present.
Sclerosing angiomatoid nodular transformation of the spleen during pregnancy : diagnostic challenges and clinical management / G. Corrado, V. Tabanelli, R. Biffi, G. Petralia, A. Tinelli, F.A. Peccatori. - In: THE JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH. - ISSN 1341-8076. - 42:8(2016), pp. 1021-1025.
|Titolo:||Sclerosing angiomatoid nodular transformation of the spleen during pregnancy : diagnostic challenges and clinical management|
|Parole Chiave:||pregnancy; sclerosing angiomatoid nodular transformation; spleen; Adult; Female; Gestational Age; Histiocytoma, Benign Fibrous; Humans; Magnetic Resonance Imaging; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pruritus; Splenic Neoplasms; Ultrasonography; Splenectomy; Obstetrics and Gynecology|
|Settore Scientifico Disciplinare:||Settore MED/36 - Diagnostica per Immagini e Radioterapia|
|Data di pubblicazione:||2016|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1111/jog.13008|
|Appare nelle tipologie:||01 - Articolo su periodico|
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