Angioedema due to acquired deficiency of the CI-inhibitor is a bridging condition between autoimmunity and lymphoproliferation. We report 32 patients with acquired CI inhibitor deficiency: 23 have anti CI-inhibitor autoantibodies; 13 have monoclonal gammopathies of unknown significance and 9 have non-Hodgkin's lymphoma. Our series suggest that different forms of B cell disorders coexist and/or evolve into each other in acquired angioedema.

Lymphoproliferative disease and acquired C1 inhibitor deficiency / R. Castelli, D.M. Lambertenghi Deliliers, L.C. Zingale, E.M. Pogliani, M. Cicardi. - In: HAEMATOLOGICA. - ISSN 0390-6078. - 92:5(2007), pp. 716-718.

Lymphoproliferative disease and acquired C1 inhibitor deficiency

R. Castelli;D.M. Lambertenghi Deliliers;L.C. Zingale;M. Cicardi
2007

Abstract

Angioedema due to acquired deficiency of the CI-inhibitor is a bridging condition between autoimmunity and lymphoproliferation. We report 32 patients with acquired CI inhibitor deficiency: 23 have anti CI-inhibitor autoantibodies; 13 have monoclonal gammopathies of unknown significance and 9 have non-Hodgkin's lymphoma. Our series suggest that different forms of B cell disorders coexist and/or evolve into each other in acquired angioedema.
Acquired; Autoantibody; C1 inhibitor; Deficiency; Lymphoproliferative
Settore MED/09 - Medicina Interna
Article (author)
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/63410
Citazioni
  • ???jsp.display-item.citation.pmc??? 15
  • Scopus 60
  • ???jsp.display-item.citation.isi??? 58
social impact