Atrial fibrillation (AF) is a common arrhythmia often associated with high thromboembolic risk. The purpose of this position paper is to provide clinicians with recommendations useful in managing some important issues regarding the use of anticoagulant therapy in patients with AF in particularly complex clinical situations. The RAND/UCLA appropriateness method, validated to combine the best available scientific evidence with the collective judgment of experts, was used to assess the judgment of an expert panel of cardiologists. To this purpose, the benefit-to-harm ratio of 37 clinical scenarios was rated. Each indication was classified as "appropriate", "uncertain", or "inappropriate" in accordance with the panelists' median score. The present document reports the results of this consensus process, which led to the development of recommendations for clinical practice on how to use anticoagulant therapy in patients with AF in complex clinical settings, including the presence of comorbidities, cardioversion, or ablation. Non-vitamin K oral anticoagulants are a valid alternative to vitamin K antagonists in preventing embolic events in patients with non-valvular AF, particularly in case of clinical complexity.
Criteri di appropriatezza nella gestione della terapia anticoagulante nel paziente complesso con fibrillazione atriale : l’opinione di un gruppo di esperti cardiologi italiani / G.L. Botto, L. Padeletti, F. Ammirati, L. Calò, V. Calvi, R. Cappato, A. Capucci, A. D'Onofrio, M. Grimaldi, F. Lombardi, M. Lunati, G. Senatore, S. Themistoclackis, G. Boriani. - In: GIORNALE ITALIANO DI CARDIOLOGIA. - ISSN 1827-6806. - 19:10(2018 Oct), pp. 591-600.
Criteri di appropriatezza nella gestione della terapia anticoagulante nel paziente complesso con fibrillazione atriale : l’opinione di un gruppo di esperti cardiologi italiani
F. Lombardi;
2018
Abstract
Atrial fibrillation (AF) is a common arrhythmia often associated with high thromboembolic risk. The purpose of this position paper is to provide clinicians with recommendations useful in managing some important issues regarding the use of anticoagulant therapy in patients with AF in particularly complex clinical situations. The RAND/UCLA appropriateness method, validated to combine the best available scientific evidence with the collective judgment of experts, was used to assess the judgment of an expert panel of cardiologists. To this purpose, the benefit-to-harm ratio of 37 clinical scenarios was rated. Each indication was classified as "appropriate", "uncertain", or "inappropriate" in accordance with the panelists' median score. The present document reports the results of this consensus process, which led to the development of recommendations for clinical practice on how to use anticoagulant therapy in patients with AF in complex clinical settings, including the presence of comorbidities, cardioversion, or ablation. Non-vitamin K oral anticoagulants are a valid alternative to vitamin K antagonists in preventing embolic events in patients with non-valvular AF, particularly in case of clinical complexity.File | Dimensione | Formato | |
---|---|---|---|
06 Botto (591-600).pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
111.96 kB
Formato
Adobe PDF
|
111.96 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.