Background and Objectives: An accurate localization is mandatory to tailor breast lumpectomy in nonpalpable cancers. The aim of this study was to compare radio-guided localization (ROLL) vs ultrasound localization of a titanium clip with collagen (TCC) in nonpalpable mass-like breast cancers. Methods: Two hundred seventy-three consecutive patients were reviewed: 64 patients were localized by TCC and 209 patients by ROLL. Propensity score-matched analysis was performed. Margin status and reintervention rates were compared. Adequacy of resection was expressed as the calculated resection ratio (CRR) considering lesion size. Loco-regional and distant recurrence rates were assessed with ROLL vs TCC. Results: No differences were found with ROLL vs TCC in clear margins (90.6% vs 89.1%; odds ratio, 0.74; P = 0.64) or reoperations (6.7% vs 1.6%; P = 0.529). ROLL allowed more tailored resections compared with TCC (adjusted CRR, 1.7 vs 2.7; P = 0.0008), particularly in lesions with associated extensive intraductal component (CRR, 3.0 vs 4.5; P = 0.017). Loco-regional recurrence occurred in 1.9% of ROLL patients vs 3.2% of TCC cases (P = 0.628). Conclusions: ROLL and TCC are equally effective to excise nonpalpable mass-like breast cancers with clear margins, providing similar loco-regional control. However, ROLL allows more tailored breast resections, particularly in lesions with the associated extensive intraductal component.
Radio-guided vs clip-guided localization of nonpalpable mass-like lesions of the breast from a screened population : a propensity score-matched study / F. Corsi, D. Bossi, F. Combi, O. Papadopoulou, R. Amadori, L. Regolo, G. Trifirò, S. Albasini, S. Mazzucchelli, L. Sorrentino. - In: JOURNAL OF SURGICAL ONCOLOGY. - ISSN 0022-4790. - 119:7(2019 Jun), pp. 916-924.
|Titolo:||Radio-guided vs clip-guided localization of nonpalpable mass-like lesions of the breast from a screened population : a propensity score-matched study|
|Parole Chiave:||breast cancer; breast-conserving surgery; clip; nonpalpable breast lesions; radio-guided occult lesion localization; Surgery; Oncology|
|Settore Scientifico Disciplinare:||Settore MED/18 - Chirurgia Generale|
|Data di pubblicazione:||giu-2019|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1002/jso.25409|
|Appare nelle tipologie:||01 - Articolo su periodico|