Frontotemporal dementia is a clinicopathological syndrome caused by progressive degeneration of the frontal lobes, anterior temporal lobes or both. A wide spectrum of cognitive, psychological and behavioural symptoms has been reported, with early disturbance of personality and social conduct, impairment of executive functions and language, while memory and visuo-spatial skills are usually preserved. Published criteria can lead to a good accuracy in the antemortem diagnosis of frontotemporal dementia with a sensitivity of 85% and a specificity of 99%. Treatment rests on the management of behavioural disturbances.

Frontotemporal dementia / C. Mariani, S. Defendi, E. Mailland, S. Pomati. - In: NEUROLOGICAL SCIENCES. - ISSN 1590-1874. - 27:Suppl. 1(2006 Mar), pp. S35-S36.

Frontotemporal dementia

C. Mariani
Primo
;
S. Defendi
Secondo
;
E. Mailland
Penultimo
;
S. Pomati
Ultimo
2006-03

Abstract

Frontotemporal dementia is a clinicopathological syndrome caused by progressive degeneration of the frontal lobes, anterior temporal lobes or both. A wide spectrum of cognitive, psychological and behavioural symptoms has been reported, with early disturbance of personality and social conduct, impairment of executive functions and language, while memory and visuo-spatial skills are usually preserved. Published criteria can lead to a good accuracy in the antemortem diagnosis of frontotemporal dementia with a sensitivity of 85% and a specificity of 99%. Treatment rests on the management of behavioural disturbances.
Cognition; Frontotemporal dementia; Tauopathies; Treatment
Settore MED/26 - Neurologia
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/63084
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