Frontotemporal dementia is a clinicopathological syndrome caused by progressive degeneration of the frontal lobes, anterior temporal lobes or both. A wide spectrum of cognitive, psychological and behavioural symptoms has been reported, with early disturbance of personality and social conduct, impairment of executive functions and language, while memory and visuo-spatial skills are usually preserved. Published criteria can lead to a good accuracy in the antemortem diagnosis of frontotemporal dementia with a sensitivity of 85% and a specificity of 99%. Treatment rests on the management of behavioural disturbances.
Frontotemporal dementia / C. Mariani, S. Defendi, E. Mailland, S. Pomati. - In: NEUROLOGICAL SCIENCES. - ISSN 1590-1874. - 27:Suppl. 1(2006 Mar), pp. S35-S36.
Frontotemporal dementia
C. MarianiPrimo
;S. DefendiSecondo
;E. MaillandPenultimo
;S. PomatiUltimo
2006
Abstract
Frontotemporal dementia is a clinicopathological syndrome caused by progressive degeneration of the frontal lobes, anterior temporal lobes or both. A wide spectrum of cognitive, psychological and behavioural symptoms has been reported, with early disturbance of personality and social conduct, impairment of executive functions and language, while memory and visuo-spatial skills are usually preserved. Published criteria can lead to a good accuracy in the antemortem diagnosis of frontotemporal dementia with a sensitivity of 85% and a specificity of 99%. Treatment rests on the management of behavioural disturbances.
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