Low molecular weight heparin has been extensively evaluated for the prevention of preeclampsia in high-risk pregnant women; however, the results from these trials have been conflicting. This review discusses the potential mechanisms of action of low molecular weight heparin for the prevention of severe preeclampsia, how to optimize the selection of high-risk women for participation in future trials, and the importance of trial standardization.

Low molecular weight heparin for the prevention of severe preeclampsia : where next? / K. Mclaughlin, R.R. Scholten, J.D. Parker, E. Ferrazzi, J.C.P. Kingdom. - In: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY. - ISSN 0306-5251. - 84:4(2018), pp. 673-678. [10.1111/bcp.13483]

Low molecular weight heparin for the prevention of severe preeclampsia : where next?

E. Ferrazzi;
2018

Abstract

Low molecular weight heparin has been extensively evaluated for the prevention of preeclampsia in high-risk pregnant women; however, the results from these trials have been conflicting. This review discusses the potential mechanisms of action of low molecular weight heparin for the prevention of severe preeclampsia, how to optimize the selection of high-risk women for participation in future trials, and the importance of trial standardization.
anticoagulants; cardiology; clinical trials; gynaecology/obstetrics; hypertension; pregnancy; Pharmacology; Pharmacology (medical)
Settore MED/40 - Ginecologia e Ostetricia
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/623328
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