Electromyography (EMG) could be useful in defining regional motor neuron vulnerability in ALS. We performed EMG in 36 sporadic ALS patients (9 with bulbar-onset and 27 with limb-onset symptoms). Active denervation was more frequent in limb than in corresponding paraspinal muscles, in the thoracic paraspinal, and in the bulbo-cervical muscles in patients with bulbar-onset symptoms. These results are consistent with a regional motor neuron vulnerability along with a nerve length-dependent liability.
|Titolo:||A tentative interpretation of electromyographic regional differences in bulbar and limb onset ALS|
SILANI, VINCENZO (Penultimo)
|Parole Chiave:||amyotrophic-later-sclerosis; disease; muscles|
|Settore Scientifico Disciplinare:||Settore MED/26 - Neurologia|
|Data di pubblicazione:||2000|
|Digital Object Identifier (DOI):||10.1212/WNL.52.3.644|
|Appare nelle tipologie:||01 - Articolo su periodico|