Electromyography (EMG) could be useful in defining regional motor neuron vulnerability in ALS. We performed EMG in 36 sporadic ALS patients (9 with bulbar-onset and 27 with limb-onset symptoms). Active denervation was more frequent in limb than in corresponding paraspinal muscles, in the thoracic paraspinal, and in the bulbo-cervical muscles in patients with bulbar-onset symptoms. These results are consistent with a regional motor neuron vulnerability along with a nerve length-dependent liability.

A tentative interpretation of electromyographic regional differences in bulbar and limb onset ALS / A. Cappellari, A. Brioschi, S. Barbieri, M. Braga, G. Scarlato, V. Silani. - In: NEUROLOGY. - ISSN 0028-3878. - 54:2(2000), pp. 644-646.

A tentative interpretation of electromyographic regional differences in bulbar and limb onset ALS

V. Silani
Penultimo
2000

Abstract

Electromyography (EMG) could be useful in defining regional motor neuron vulnerability in ALS. We performed EMG in 36 sporadic ALS patients (9 with bulbar-onset and 27 with limb-onset symptoms). Active denervation was more frequent in limb than in corresponding paraspinal muscles, in the thoracic paraspinal, and in the bulbo-cervical muscles in patients with bulbar-onset symptoms. These results are consistent with a regional motor neuron vulnerability along with a nerve length-dependent liability.
amyotrophic-later-sclerosis; disease; muscles
Settore MED/26 - Neurologia
2000
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/61340
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