Mass spectrometric methods of identification and measurement are pivotal to investigate the multifaceted biological role of ceramides and the dose-effect relationship of pharmaceuticals that modulate ceramide flux. Triple-quadrupole tandem MS embodies the highest flexibility to discover, identify and measure expected and unexpected molecular species, and an unprecedented scan mode is presented
Ceramidome plasticity through iso-energetic precursor and neutral loss discovery scans / F.M. Rubino, M. Dei Cas, J. Rizzo, P. Signorelli, R. Ghidoni, R.C. Paroni - In: XXII International Mass Spectrometry Conference : abstract book / [a cura di] G. Giorgi. - Prima edizione. - Firenze : International Mass Spectrometry Foundation, 2018 Nov. - ISBN 9788890738852. - pp. 1138-1139 (( Intervento presentato al 22. convegno International mass spectrometry conference tenutosi a Firenze nel 2018.
Ceramidome plasticity through iso-energetic precursor and neutral loss discovery scans
F.M. RubinoPrimo
Membro del Collaboration Group
;M. Dei CasSecondo
;J. Rizzo;P. Signorelli;R. GhidoniPenultimo
;R.C. ParoniUltimo
2018-11
Abstract
Mass spectrometric methods of identification and measurement are pivotal to investigate the multifaceted biological role of ceramides and the dose-effect relationship of pharmaceuticals that modulate ceramide flux. Triple-quadrupole tandem MS embodies the highest flexibility to discover, identify and measure expected and unexpected molecular species, and an unprecedented scan mode is presented
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