The risk of opportunistic infections and inefficient immune reconstitution in advanced naive HIV+ patients starting HAART are critical issues in the management of HIV infection. We studied the effects of IL-2 adjuvant therapy in favoring a rapid CD4 cell rescue, shortening the time frame at highest risk of HIV-related clinical events in patients with severe immune impairment.
Clinical effect of interleukin-2 (IL-2) immuno-adjuvant treatment in HIV+ advanced naïve patients / C. Tincati, M. Cesari, L. Meroni, F. Bai, G.M. Bellistrì, M. Galli, M.E. Moroni, A. d'Arminio Monforte, G.M. Marchetti. - In: JOURNAL OF THE INTERNATIONAL AIDS SOCIETY. - ISSN 1758-2652. - 2008:11(2008), pp. 1-1. ((Intervento presentato al 9. convegno International Congress on drug therapy in HIV infection tenutosi a Glasgow nel 2008 [10.1186/1758-2652-11-S1-P1].
Clinical effect of interleukin-2 (IL-2) immuno-adjuvant treatment in HIV+ advanced naïve patients
C. Tincati;M. Cesari;F. Bai;M. Galli;A. d'Arminio Monforte;
2008
Abstract
The risk of opportunistic infections and inefficient immune reconstitution in advanced naive HIV+ patients starting HAART are critical issues in the management of HIV infection. We studied the effects of IL-2 adjuvant therapy in favoring a rapid CD4 cell rescue, shortening the time frame at highest risk of HIV-related clinical events in patients with severe immune impairment.
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