N-Acetylneuraminic acid is transformed into its until now unavailable and rather unwieldy 1,7-lactone, via the manageable 2-benzyloxycarbonyl N-acetylneuraminic acid 1,7-lactone which generates the free lactone in quantitative yield by hydrogenolysis.
The first synthesis of N-Acetylneuraminic acid 1,7 Lactone / R. Colombo, M. Anastasia, P. Rota, P. Allevi. - In: CHEMICAL COMMUNICATIONS. - ISSN 1359-7345. - 2008:43(2008 Oct 20), pp. 5517-5519.
The first synthesis of N-Acetylneuraminic acid 1,7 Lactone
M. AnastasiaSecondo
;P. Rota;P. AlleviPenultimo
2008
Abstract
N-Acetylneuraminic acid is transformed into its until now unavailable and rather unwieldy 1,7-lactone, via the manageable 2-benzyloxycarbonyl N-acetylneuraminic acid 1,7-lactone which generates the free lactone in quantitative yield by hydrogenolysis.File in questo prodotto:
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