Background: International standard panels of single nucleotide polymorphisms (SNPs) have replaced microsatellites in several species for parentage assessment and assignment (PA) purposes. However, such a resource is still lacking in goats. The application of a cheap tool for PA would help the management of goat populations by improving the reliability of pedigree registration and, consequently, allow a better implementation of breeding schemes or conservation programs. Results: Using data from the current GoatSNP50 chip, starting from a worldwide dataset of more than 4000 animals belonging to more than 140 breeds and populations from the AdaptMap initiative, we selected a panel of 195 SNPs. The assignment rate of this panel was up to 100% on an additional dataset that included 2000 Alpine and Saanen animals and highly related candidate sires. Conclusions: In this study, we defined a highly informative SNP panel, which will be publicly available to worldwide breeders and laboratories. Its development on such a large number of breeds and populations, together with validation on a second set of cosmopolitan breeds, makes it a promising and important genomic tool for the goat species.
Functional SNP panel for parentage assessment and assignment in worldwide goat breeds / A. Talenti, I. Palhière, F. Tortereau, G. Pagnacco, A. Stella, E.L. Nicolazzi, P. Crepaldi, G. Tosser-Klopp. - In: GENETICS SELECTION EVOLUTION. - ISSN 0999-193X. - 50(2018 Nov 19), pp. 55.1-55.7.
|Titolo:||Functional SNP panel for parentage assessment and assignment in worldwide goat breeds|
CREPALDI, PAOLA (Corresponding)
|Settore Scientifico Disciplinare:||Settore AGR/17 - Zootecnica Generale e Miglioramento Genetico|
|Data di pubblicazione:||19-nov-2018|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1186/s12711-018-0423-9|
|Appare nelle tipologie:||01 - Articolo su periodico|