Little is known about the structure and distinguishing features of core promoters in Plasmodium falciparum. In this work, we describe the first method to computationally identify core promoters in this AT-rich genome. This prediction algorithm uses solely DNA physicochemical properties as descriptors. Our results add to a growing body of evidence that a physicochemical code for eukaryotic genomes plays a crucial role in core promoter recognition.
Core promoters are predicted by their distinct physicochemical properties in the genome of Plasmodium falciparum / K. Brick, J. Watanabe, E. Pizzi. - In: GENOME BIOLOGY. - ISSN 1474-7596. - 9:12(2008 Dec), pp. R178.R178.1-R178.R178.16. [10.1186/gb-2008-9-12-r178]
Core promoters are predicted by their distinct physicochemical properties in the genome of Plasmodium falciparum
K. BrickPrimo
;
2008
Abstract
Little is known about the structure and distinguishing features of core promoters in Plasmodium falciparum. In this work, we describe the first method to computationally identify core promoters in this AT-rich genome. This prediction algorithm uses solely DNA physicochemical properties as descriptors. Our results add to a growing body of evidence that a physicochemical code for eukaryotic genomes plays a crucial role in core promoter recognition.
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