Alkenes possessing a C=C double bond adjacent to an aromatic ring were cleaved to yield the corresponding carbonyl compounds by use of molecular oxygen as the sole oxidant and a cell-free extract of the wood-degrading fungus Trametes hirsuta FCC 047 as catalyst. The oxygen pressure required was optimized. Special adapted equipment allowed 96 reactions to be performed in parallel under controlled oxygen pressure. A broad spectrum of aryl-alkenes was successfully converted into the corresponding ketones/aldehydes with excellent chemoselectivity under a controlled oxygen atmosphere (2 bar).
|Titolo:||Biocatalytic cleavage of alkenes with O-2 and Trametes hirsuta G FCC 047|
MUTTI, FRANCESCO (Secondo)
|Parole Chiave:||"Green" chemistry; Alkenes; Biocatalysis; Oxidation; Trametes hirsuta|
|Settore Scientifico Disciplinare:||Settore CHIM/01 - Chimica Analitica|
|Data di pubblicazione:||2008|
|Digital Object Identifier (DOI):||10.1002/ejoc.200800261|
|Appare nelle tipologie:||01 - Articolo su periodico|