Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localized or generalized bullous lesions. In up to 20% of affected patients blister may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions, and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on the quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged. This guideline for the treatment of bullous pemphigoid has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum (EDF) in collaboration with the European Academy of Dermatology and Venereology (EADV). It summarizes evidence-based and expert-based recommendations (S2 level).

Bullous pemphigoid : Italian guidelines adapted from the EDF/EADV guidelines / E. Cozzani, A.V. Marzano, M. Caproni, C. Feliciani, P. Calzavara-Pinton, M. Alaibac, E. Antiga, M. Arisi, D. Assalve, L. Atzori, G. Babino, A. Balato, N. Balato, T. Barbagallo, A.B. Fortina, E. Berardesca, E. Berti, A. Borghi, V. Brazzelli, M.B. Brumana, C. Brusati, S. Caccavale, G. Caldarola, A. Campanati, R.D.C. Caro, I. Coati, A. Conti, A. Costanzo, A. Dattola, C. De Simone, A. Di Cesare, V. Di Lernia, G.M. Di Zenzo, L. Fania, G. Filosa, R. Filotico, M. Fusano, A.G. Galluccio, G. Ganzetti, P. Gisondi, F. Guarneri, K. Hansel, S. Javor, M. Laplaca, G. Liberati, V. Lora, G. Merlo, M.R. Nasca, A. Nigro, C. Noal, A. Offidani, M. Papini, A. Parodi, A. Patrizi, A. Peserico, S. Piaserico, F. Prignano, P. Quaglino, M. Rossi, R. Satta, D. Schena, P. Sena, O. Simonetti, T.R. Stan, L. Stingeni, M. Talamonti, S. Tavecchio, L. Tognetti, A. Vascellaro, C. Vassallo, M. Venturini, A. Zampetti, A. Zanca. - In: GIORNALE ITALIANO DI DERMATOLOGIA E VENEREOLOGIA. - ISSN 0392-0488. - 153:3(2018), pp. 305-315.

Bullous pemphigoid : Italian guidelines adapted from the EDF/EADV guidelines

A.V. Marzano;E. Berti;G. Ganzetti;
2018

Abstract

Bullous pemphigoid is the most common autoimmune subepidermal blistering disease of the skin and mucous membranes. This disease typically affects the elderly and presents with itch and localized or generalized bullous lesions. In up to 20% of affected patients blister may be completely absent, and only excoriations, prurigo-like lesions, eczematous lesions, urticated lesions, and/or infiltrated plaques are observed. The disease is significantly associated with neurological disorders. The morbidity of bullous pemphigoid and its impact on the quality of life are significant. So far, a limited number of national treatment guidelines have been proposed, but no common European consensus has emerged. This guideline for the treatment of bullous pemphigoid has been developed by an Italian group of experts taking in account the Italian legislation and local pharmacological governance. Guidelines are adapted from the original article under the guidance of the European Dermatology Forum (EDF) in collaboration with the European Academy of Dermatology and Venereology (EADV). It summarizes evidence-based and expert-based recommendations (S2 level).
Bullous pemphigoid; Guideline; Quality of life; Rare diseases; 2708
Settore MED/35 - Malattie Cutanee e Veneree
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/590648
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