Secondary hyperparathyroidism (SHP) is one of the most challenging complications in the most advanced stages of end-stage renal disease. In the last decade, newly available medical tools have greatly increased the possibilities for controlling SHP. However, one of these tools, cinacalcet, has not yet been approved for its use in transplanted patients and the evidence for its safety in this clinical setting is still incomplete. For these reasons, many questions still remain open for the clinical nephrologist: when to consider a parathyroidectomy (PTX) in a patient on a waiting list for kidney transplant (KTx); when to recommend PTX after KTx; when could a regression of parathyroid hyperplasia be expected at any time after KTx. In the present paper, we will briefly deal with these questions in the light of an unusual clinical case.

Current indications to parathyroidectomy in CKD patients before and after renal transplantation / P. Messa, A. Regalia, C.M. Alfieri, D. Cresseri, L. Forzenigo, M.T. Gandolfo, M.P. Rastaldi. - In: JN. JOURNAL OF NEPHROLOGY. - ISSN 1121-8428. - 26:6(2013), pp. 1025-1032.

Current indications to parathyroidectomy in CKD patients before and after renal transplantation

Messa, Piergiorgio;Regalia, Anna;Alfieri, Carlo Maria;
2013

Abstract

Secondary hyperparathyroidism (SHP) is one of the most challenging complications in the most advanced stages of end-stage renal disease. In the last decade, newly available medical tools have greatly increased the possibilities for controlling SHP. However, one of these tools, cinacalcet, has not yet been approved for its use in transplanted patients and the evidence for its safety in this clinical setting is still incomplete. For these reasons, many questions still remain open for the clinical nephrologist: when to consider a parathyroidectomy (PTX) in a patient on a waiting list for kidney transplant (KTx); when to recommend PTX after KTx; when could a regression of parathyroid hyperplasia be expected at any time after KTx. In the present paper, we will briefly deal with these questions in the light of an unusual clinical case.
Cinacalcet; Hypercalcemia; Parathyroidectomy; Renal transplant; Secondary hyperparathyroidism
Settore MED/14 - Nefrologia
JN. JOURNAL OF NEPHROLOGY
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/588840
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