The degeneration of articular cartilage represents an ongoing challenge at the clinical and basic level. Tissue engineering and regenerative medicine using stem/progenitor cells have emerged as valid alternatives to classical reparative techniques. This review offers a brief introduction and overview of the field, highlighting a number of tissue sources for stem/progenitor cell populations. Emphasis is given to recent developments in both clinical and basic sciences. The relative strengths and weaknesses of each tissue type are discussed.

The application of stem cells from different tissues to cartilage repair / J.N. Fisher, I. Tessaro, T. Bertocco, G.M. Peretti, L. Mangiavini. - In: STEM CELLS INTERNATIONAL. - ISSN 1687-9678. - 2017(2017), pp. 2761678.1-2761678.14. [10.1155/2017/2761678]

The application of stem cells from different tissues to cartilage repair

I. Tessaro;G.M. Peretti;L. Mangiavini
2017

Abstract

The degeneration of articular cartilage represents an ongoing challenge at the clinical and basic level. Tissue engineering and regenerative medicine using stem/progenitor cells have emerged as valid alternatives to classical reparative techniques. This review offers a brief introduction and overview of the field, highlighting a number of tissue sources for stem/progenitor cell populations. Emphasis is given to recent developments in both clinical and basic sciences. The relative strengths and weaknesses of each tissue type are discussed.
Human bone-marrow; human articular chondrocytes; randomized controlled-trial; thickness chondral defects; mesenchymal stromal cells; hyaluronic-acid hydrogel; high tibial osteotomy; proof-of-concept; intraarticular injection; in-vivo
Settore MED/33 - Malattie Apparato Locomotore
Article (author)
File in questo prodotto:
File Dimensione Formato  
2761678.pdf

accesso aperto

Tipologia: Publisher's version/PDF
Dimensione 1.99 MB
Formato Adobe PDF
1.99 MB Adobe PDF Visualizza/Apri
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/588283
Citazioni
  • ???jsp.display-item.citation.pmc??? 7
  • Scopus 17
  • ???jsp.display-item.citation.isi??? 16
social impact