The limited fossil resources availability and the climate change are raising wide interest between the scientific researchers and the civil community. Among the several subjects, the production of bulk chemicals from renewable sources is one of the great challenge that researchers are facing. Concerning this theme, adipic acid (AdA) production from wood biomass is one of the most important topic due to the large amount of AdA consumed and the market growth, in particular for the production of polyamides (Nylon 6,6). Bio-AdA can be produced from t,t-muconic acid (MA), a metabolic intermediate of the catechol ortho-cleavage pathway.1 In nature, microorganisms displaying this pathway are quite common and they can accumulate at least 13.5 g/l of MA as sodium muconate2. The so produced sodium muconate is then converted to AdA with a heterogeneous hydrogenation chemical reaction. Using mild operating conditions (70°C and hydrogen pressure 4 bar) and commercial catalyst (Pt/AC 5% wt or Pd/AC 5% wt) in 1 hour a full conversion and a complete selectivity toward AdA is achieved3. MA coming from the fermenter needs a purification step due to the high purity grade required for the market. The purification process consists in an acidification and crystallization steps, that transform sodium muconate into muconic acid, separating this chemical from all the compounds used in the fermenter. Considering water as hydrogenation reaction media, unfortunately MA is less soluble than sodium muconate. On the basis of these considerations different hydrogenation reactions were performed varying the operating conditions both on muconic acid and sodium muconate. The results reveal a different behavior during hydrogenation reaction performed at 70°C at different hydrogen pressures. Pd/AC 5%wt commercial catalyst was used, maintaining the catalyst/substrate ratio equal to 200:1 (mol basis). The results are reported in Fig.1. Using t,t-MA than Na-muconate a higher activity and selectivity to AdA have been observed. Moreover, the effect of reaction conditions, such as reaction temperature, hydrogen pressure and catalyst amount have been investigated.
Muconic acid and sodium muconate hydrogenation to bio-adipic acid / S. Capelli, C.L. Bianchi, L. Prati, A. Villa, C. Pirola. ((Intervento presentato al 20. convegno Congresso Nazionale della Divisione di Chimica Industriale tenutosi a Milano nel 2018.
|Titolo:||Muconic acid and sodium muconate hydrogenation to bio-adipic acid|
|Data di pubblicazione:||2018|
|Settore Scientifico Disciplinare:||Settore ING-IND/25 - Impianti Chimici|
Settore CHIM/04 - Chimica Industriale
Settore CHIM/03 - Chimica Generale e Inorganica
|Enti collegati al convegno:||SCI|
|Citazione:||Muconic acid and sodium muconate hydrogenation to bio-adipic acid / S. Capelli, C.L. Bianchi, L. Prati, A. Villa, C. Pirola. ((Intervento presentato al 20. convegno Congresso Nazionale della Divisione di Chimica Industriale tenutosi a Milano nel 2018.|
|Appare nelle tipologie:||14 - Intervento a convegno non pubblicato|