Susceptibility to HIV infection is widely different among individuals, and it is known that individuals can be identified who are repeatedly exposed to HIV but in whom neither infection nor disease are seen. The possibility that sheer luck is not the only determinant of this phenomenon begun to be considered in 1989 when it was reported that T cell responses to HIV proteins could be detected in antibody-negative sexual partners of known HIV-positive men. In this review, we will summarize the body of knowledge that stemmed from that first observation.

Not just sheer luck! Immune correlates of protection against HIV-1 infection / L. Piacentini, C. Fenizia, V. Naddeo, M. Clerici. - In: VACCINE. - ISSN 0264-410X. - 26:24(2008 Jun 06), pp. 3002-3007.

Not just sheer luck! Immune correlates of protection against HIV-1 infection

L. Piacentini
Primo
;
C. Fenizia
Secondo
;
V. Naddeo
Penultimo
;
M. Clerici
Ultimo
2008-06-06

Abstract

Susceptibility to HIV infection is widely different among individuals, and it is known that individuals can be identified who are repeatedly exposed to HIV but in whom neither infection nor disease are seen. The possibility that sheer luck is not the only determinant of this phenomenon begun to be considered in 1989 when it was reported that T cell responses to HIV proteins could be detected in antibody-negative sexual partners of known HIV-positive men. In this review, we will summarize the body of knowledge that stemmed from that first observation.
AIDS ; HIV-exposed seronegative individuals ; Immunology ; Resistance to infection ; Immune correlates of protection
Settore MED/04 - Patologia Generale
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/58664
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