We studied the predictive value of self-reported adherence and plasma drug concentrations on virological rebound to HAART. Among 238 participants in the AdICoNA study who had viral load ≤500 copies/ml, 42 (17.6%) experienced virological rebound by 96 weeks. Both self-reported non-adherence and sub-optimal concentration were independently associated with a higher risk of virological rebound.
Relative prognostic value of self-reported adherence and plasma NNRTI/PI concentrations to predict virological rebound in patients initially responding to HAART / A. Antinori, A. Cozzi-Lepri, A. Ammassari, M.P. Trotta, D. Nauwelaers, R. Murri, S. Melzi, P. Narciso, P. Nasta, M. Zaccarelli, P. Santopadre, J. Vecchiet, C.M. Izzo, A. D’Arminio Monforte, Ad.I.Co.N.A. Study Group. - In: ANTIVIRAL THERAPY. - ISSN 1359-6535. - 9:2(2004), pp. 291-294.
Relative prognostic value of self-reported adherence and plasma NNRTI/PI concentrations to predict virological rebound in patients initially responding to HAART
A. D’Arminio MonforteUltimo
;
2004
Abstract
We studied the predictive value of self-reported adherence and plasma drug concentrations on virological rebound to HAART. Among 238 participants in the AdICoNA study who had viral load ≤500 copies/ml, 42 (17.6%) experienced virological rebound by 96 weeks. Both self-reported non-adherence and sub-optimal concentration were independently associated with a higher risk of virological rebound.
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