Background. Greenhouses are a peculiar indoor working environment, where mixtures of pesticides, variable according to crop and season, are used. Occupational exposure measurement is thus difficult and only seldom performed, thus making task-based semiquantitative estimates an attractive tool for exposure and health risk assessment. Objective. To provide a user-friendly, reliable description of risk through a minimum set of exposure indicators of work conditions and absorbed doses. Methods. a: indicators were chosen according to scientific and agronomic literature and task analysis. Different exposure conditions were ranked by attribution of scores (high, intermediate, low) and a semiquantitative algorithm was implemented to model individual exposure. b: Risk Profile was applied to literature exposure studies to compare the agreement of model calculations to risk assessed by field measurements. c: a targeted study was performed to evaluate the agreement of model estimates to measured exposure of greenhouse workers using chlorpyrifos-methyl. Results. greenhouse workers resulted exposed to airborne concentrations below established safety standards; dermal exposure ranged from GM 20 ng/cm2 outside clothing to GM 2ng/cm2 under clothing (Range: 0.2-4100 ng/cm2). Total Exposure Index was estimated: variables affecting pesticide exposure levels for each task were highlighted. These estimates are in line with published studies and with the measurements performed in the exposed workers. Conclusions: Exposure measurement, indirect assessment and derived Risk Profiles provide a reliable description of working conditions through a minimum set of indicators and with minimal use of expensive workplace or biological monitoring, thus qualifying as promising tools for pesticide risk evaluation in agricultural settings.
Preparation and validation of exposure and risk profiles for pestcide use in greenhouses / C. Colosio, E. Ariano, M. Carcano, A. Chiodini, S. Fustinoni, C. Somaruga, F. Travaglini, F. Vellere, F. M. Rubino, L. Settimi, F. Toffoletto, G. Brambilla, A. Colombi. - In: TOXICOLOGY LETTERS. - ISSN 0378-4274. - 180:suppl 1(2008 Oct 05), pp. S26-S26. ((Intervento presentato al 45. convegno EUROTOX 2008 tenutosi a Rhodes, Greece nel 2008.
|Titolo:||Preparation and validation of exposure and risk profiles for pestcide use in greenhouses|
|Parole Chiave:||Pesticides ; exposure assessment ; exposure modelling|
|Settore Scientifico Disciplinare:||Settore VET/05 - Malattie Infettive degli Animali Domestici|
Settore MED/44 - Medicina del Lavoro
|Data di pubblicazione:||5-ott-2008|
|Enti collegati al convegno:||International Societies of Toxicology|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.toxlet.2008.06.849|
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