FLAIR and diffusion-weighted MRI were obtained twice (mean interval 20 +/- 4 months) in 10 patients with leukoaraiosis. At follow-up, visual extension of leukoaraiosis was unchanged, whereas the median of whole brain apparent diffusion coefficient (WB-ADC) histogram was increased (p= 0.008) and brain volume index (BVI) was decreased (p = 0.006). WB-ADC histogram and BVI are sensitive to leukoaraiosis and might be considered for monitoring progression of the disease.
Longitudinal evaluation of leukoaraiosis with whole brain ADC histograms / M. Mascalchi, M. Moretti, R. Della Nave, F. Lolli, C. Tessa, G. Carlucci, L. Bartolini, G. Pracucci, L. Pantoni, M. Filippi, D. Inzitari. - In: NEUROLOGY. - ISSN 0028-3878. - 59:6(2002 Sep 24), pp. 938-940.
Longitudinal evaluation of leukoaraiosis with whole brain ADC histograms
L. Pantoni
;
2002
Abstract
FLAIR and diffusion-weighted MRI were obtained twice (mean interval 20 +/- 4 months) in 10 patients with leukoaraiosis. At follow-up, visual extension of leukoaraiosis was unchanged, whereas the median of whole brain apparent diffusion coefficient (WB-ADC) histogram was increased (p= 0.008) and brain volume index (BVI) was decreased (p = 0.006). WB-ADC histogram and BVI are sensitive to leukoaraiosis and might be considered for monitoring progression of the disease.
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