Post-kala-azar dermal leishmaniasis (PKDL) is a complication of visceral leishmaniasis (VL) observed mainly in Sudan and India where it follows treated VL in 50% and 10% of cases, respectively. We report a 46-year-old patient with acquired immune deficiency syndrome who, 7 months after diagnosis of VL, developed PKDL and uveal leishmaniasis following HAART-induced immune recovery. In southern Europe PKDL seems to be an emerging clinical presentation among human immunodeficiency virus (HIV)-infected patients experiencing HAART-induced immune recovery after a previous diagnosis of VL. The best treatment among HIV-infected patients remains to be determined.
|Titolo:||Post-kala-azar dermal leishmaniasis as an immune reconstitution inflammatory syndrome in a patient with acquired immune deficiency syndrome|
|Parole Chiave:||HAART; Human immunodeficiency virus; Immune reconstitution inflammatory syndrome; Leishmania infantum; Post-kala-azar dermal leishmaniasis|
|Settore Scientifico Disciplinare:||Settore MED/17 - Malattie Infettive|
|Data di pubblicazione:||nov-2007|
|Digital Object Identifier (DOI):||10.1111/j.1365-2133.2007.08157.x|
|Appare nelle tipologie:||01 - Articolo su periodico|