Cerebral amyloid angiopathy (CAA) is a contributor to cognitive impairment in the elderly. We hypothesized that the posterior cortical predilection of CAA would cause visual-processing impairment. We systematically evaluated visuospatial abilities in 22 non-demented CAA patients. Neurocognitive evaluation demonstrated visuoperceptual impairment (23 on Benton Facial Recognition Test [BFRT] and 13.6 on Benton Judgment of Line Orientation Test [BJLO]). BFRT was inversely correlated with white matter hyperintensities volume and BJLO with parietal cerebral microbleeds. This pilot study highlights the presence of visual-processing deficits in CAA. The impairment could be related to global disease severity in addition to local brain injury.
|Titolo:||Visuospatial Functioning in Cerebral Amyloid Angiopathy : a Pilot Study|
|Parole Chiave:||Cerebral amyloid angiopathy; Neuroimaging markers; Neuropsychological assessment; Visuospatial functioning; Aged; Brain; Cerebral Amyloid Angiopathy; Cerebral Hemorrhage; Cross-Sectional Studies; Female; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Neuropsychological Tests; Organ Size; Perceptual Disorders; Pilot Projects; Recognition (Psychology); White Matter; Spatial Processing; Visual Perception; Clinical Psychology; Geriatrics and Gerontology; Psychiatry and Mental Health|
|Settore Scientifico Disciplinare:||Settore MED/26 - Neurologia|
|Data di pubblicazione:||2017|
|Digital Object Identifier (DOI):||10.3233/JAD-160927|
|Appare nelle tipologie:||01 - Articolo su periodico|