Monooxygenation of styrene derivs. using a recombinant E. coli biocatalyst represents an efficient way to prep. the corresponding oxiranes. The present work examines the electronic and geometric effects of the ring substituents and reveals an enzymic activity characterized by relaxed specificity and high stereoselectivity.

Bacterial monooxygenase mediated preparation of nonracemic chiral oxiranes: study of the effects of substituent nature and position / S. Bernasconi, F. Orsini, G. Sello, P. Di Gennaro. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 15:10(2004 May 24), pp. 1603-1606. [10.1016/j.tetasy.2004.04.005]

Bacterial monooxygenase mediated preparation of nonracemic chiral oxiranes: study of the effects of substituent nature and position

S. Bernasconi
Primo
;
F. Orsini
Secondo
;
G. Sello
Penultimo
;
2004

Abstract

Monooxygenation of styrene derivs. using a recombinant E. coli biocatalyst represents an efficient way to prep. the corresponding oxiranes. The present work examines the electronic and geometric effects of the ring substituents and reveals an enzymic activity characterized by relaxed specificity and high stereoselectivity.
recombinant escherichia-coli; pseudomonas-fluorescens st; nonaqueous-phase liquids; styrene monooxygenase; enantiopure epoxides; diodegradation; bioreactors; phenanthrene; degradation; system
Settore CHIM/06 - Chimica Organica
24-mag-2004
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/5701
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