Monooxygenation of styrene derivs. using a recombinant E. coli biocatalyst represents an efficient way to prep. the corresponding oxiranes. The present work examines the electronic and geometric effects of the ring substituents and reveals an enzymic activity characterized by relaxed specificity and high stereoselectivity.
Bacterial monooxygenase mediated preparation of nonracemic chiral oxiranes: study of the effects of substituent nature and position / S. Bernasconi, F. Orsini, G. Sello, P. Di Gennaro. - In: TETRAHEDRON-ASYMMETRY. - ISSN 0957-4166. - 15:10(2004 May 24), pp. 1603-1606. [10.1016/j.tetasy.2004.04.005]
Bacterial monooxygenase mediated preparation of nonracemic chiral oxiranes: study of the effects of substituent nature and position
S. BernasconiPrimo
;F. OrsiniSecondo
;G. SelloPenultimo
;
2004
Abstract
Monooxygenation of styrene derivs. using a recombinant E. coli biocatalyst represents an efficient way to prep. the corresponding oxiranes. The present work examines the electronic and geometric effects of the ring substituents and reveals an enzymic activity characterized by relaxed specificity and high stereoselectivity.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
1-s2.0-S0957416604002630-main.pdf
accesso riservato
Tipologia:
Publisher's version/PDF
Dimensione
252.5 kB
Formato
Adobe PDF
|
252.5 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
