RP is the most common manifestation of SSc and a major cause of disease-related morbidity. This review provides a detailed appraisal of the patient experience of SSc-RP and potential implications for disease classification, patient-reported outcome instrument development and SSc-RP clinical trial design. The review explores the clinical features of SSc-RP, the severity and burden of SSc-RP symptoms and the impact of SSc-RP on function, work and social participation, body image dissatisfaction and health-related quality of life in SSc. Where management of SSc-RP is concerned, the review focuses on the 'patient experience' of interventions for SSc-RP, examining geographic variation in clinical practice and potential barriers to the adoption of treatment recommendations concerning best-practice management of SSc-RP. Knowledge gaps are highlighted that could form the focus of future research. A more thorough understanding of the patient experience could support the development of novel reported outcome instruments for assessing SSc-RP.
|Titolo:||The patient experience of Raynaud's phenomenon in systemic sclerosis|
INGEGNOLI, FRANCESCA ANNA (Penultimo)
|Parole Chiave:||systemic sclerosis; Raynaud’s phenomenon; patient experience; health-related quality of life; disability; function; impact Rheumatology key|
|Settore Scientifico Disciplinare:||Settore MED/16 - Reumatologia|
|Data di pubblicazione:||12-mar-2018|
|Digital Object Identifier (DOI):||10.1093/rheumatology/key026|
|Appare nelle tipologie:||01 - Articolo su periodico|