Lymphedema is mainly characterized by swelling, fibrosis, and nonpitting edema. The aim of this study was evaluation of the long-term (10 years) effects of autologus lymphatic tissue implant in lymphedema. Lymphatic tissue from 9 patients (harvested form the same patient in areas not affected by lymphedema) was reimplanted into the affected limb, and these patients were followed for 10 years. Lymph nodes were harvested at the neck, axillary, or inguinal space (contralateral limb). Results showed that limb volume was decreased in the treatment group vs. controls. In ultrasound, black, low density, lymphatic spaces were visible in 100% of patients at inclusion but in only 23% of these subjects at 10 years. Thus, this early report proposes a new, minimally invasive method to improve lymphedema. Studies in progress will indicate the role of lymphatic transplant in the management of lymphedema and the best indications for this method.
|Titolo:||Lymphatic tissue transplant in lymphedema--a minimally invasive, outpatient, surgical method : a 10-year follow-up pilot study|
|Autori interni:||IPPOLITO, EDMONDO|
|Parole Chiave:||Autologous tissue transplant; Edema; Leg swelling; Lymph nodes; Lymphatic tissue; Lymphedema|
|Settore Scientifico Disciplinare:||Settore MED/22 - Chirurgia Vascolare|
|Data di pubblicazione:||feb-2008|
|Digital Object Identifier (DOI):||10.1177/0003319707308564|
|Appare nelle tipologie:||01 - Articolo su periodico|