Malignant pleural mesothelioma is a neoplasm characterized by an increasing incidence and poor prognosis. When surgical treatment cannot be performed, systemic chemotherapy remains the main therapeutic option. Here we report the case of a 41-year-old female patient with epithelioid malignant pleural mesothelioma who was treated with carboplatin and pemetrexed despite her critical condition. She showed an impressive response to this first-line chemotherapy and, after disease progression, to further chemotherapy with gemcitabine and vinorelbine. She is still alive, with unexpectedly long-lasting survival.
An unusually large pleural mesothelioma with an outstanding clinical response and long lasting survival: a case report and literature review / N. Zilembo, M. Vitali, F. Pietrantonio, M. Platania, M. Del Vecchio, E. Bajetta. - In: TUMORI. - ISSN 0300-8916. - 96:6(2010), pp. 1031-1034.
An unusually large pleural mesothelioma with an outstanding clinical response and long lasting survival: a case report and literature review
F. Pietrantonio;
2010
Abstract
Malignant pleural mesothelioma is a neoplasm characterized by an increasing incidence and poor prognosis. When surgical treatment cannot be performed, systemic chemotherapy remains the main therapeutic option. Here we report the case of a 41-year-old female patient with epithelioid malignant pleural mesothelioma who was treated with carboplatin and pemetrexed despite her critical condition. She showed an impressive response to this first-line chemotherapy and, after disease progression, to further chemotherapy with gemcitabine and vinorelbine. She is still alive, with unexpectedly long-lasting survival.
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