The additive under assessment, manganese hydroxychloride, contains ≥ 45% manganese (Mn). Manganese hydroxychloride is a safe source of manganese for all target species when used up to the maximum level of total manganese in complete feed authorised in the EU (Fish 100 (total) and Other species 150 (total) mg Mn/kg feedingstuffs). Manganese hydroxychloride would substitute for other manganese sources in feed. It does not differently affect tissue deposition compared to manganese sulphate. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concludes that the use of manganese hydroxychloride in animal nutrition is safe for the consumers, provided the maximum authorised manganese content in complete feed is respected. In the absence of specific data, the FEEDAP Panel cannot conclude on the safety for the user when handling the additive. The use of manganese hydroxychloride in animal nutrition for all animal species is not expected to pose a risk to the environment. Manganese hydroxychloride is considered a source of bioavailable manganese as indicated by a dose-dependent increase of manganese deposition in bone and liver based on two studies on chickens for fattening. The FEEDAP Panel concludes that the additive is efficacious in meeting the manganese requirements for all animal species/categories.

Safety and efficacy of manganese hydroxychloride as feed additive for all animal species / G. Aquilina, G. Azimonti, V. Bampidis, M. de Lourdes Bastos, G. Bories, A. Chesson, P.S. Cocconcelli, G. Flachowsky, J. Gropp, B. Kolar, M. Kouba, S. Lopez Puente, M. Lopez-Alonso, A. Mantovani, B. Mayo, F. Ramos, G. Rychen, M. Saarela, R.E. Villa, R.J. Wallace, P. Wester. - In: EFSA JOURNAL. - ISSN 1831-4732. - 14:5(2016), pp. 4474.1-4474.15. [10.2903/j.efsa.2016.4474]

Safety and efficacy of manganese hydroxychloride as feed additive for all animal species

R.E. Villa;
2016

Abstract

The additive under assessment, manganese hydroxychloride, contains ≥ 45% manganese (Mn). Manganese hydroxychloride is a safe source of manganese for all target species when used up to the maximum level of total manganese in complete feed authorised in the EU (Fish 100 (total) and Other species 150 (total) mg Mn/kg feedingstuffs). Manganese hydroxychloride would substitute for other manganese sources in feed. It does not differently affect tissue deposition compared to manganese sulphate. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concludes that the use of manganese hydroxychloride in animal nutrition is safe for the consumers, provided the maximum authorised manganese content in complete feed is respected. In the absence of specific data, the FEEDAP Panel cannot conclude on the safety for the user when handling the additive. The use of manganese hydroxychloride in animal nutrition for all animal species is not expected to pose a risk to the environment. Manganese hydroxychloride is considered a source of bioavailable manganese as indicated by a dose-dependent increase of manganese deposition in bone and liver based on two studies on chickens for fattening. The FEEDAP Panel concludes that the additive is efficacious in meeting the manganese requirements for all animal species/categories.
nutritional additive; compounds of trace elements; manganese; manganese hydroxychloride; safety; efficacy
Settore VET/07 - Farmacologia e Tossicologia Veterinaria
2016
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/561322
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