PURPOSE: To describe the imaging features of choroidal neovascularization (CNV) associated with choroidal nevus using optical coherence tomography angiography (OCT-A) imaging. METHODS: Retrospective observational case series. Patients with CNV secondary to choroidal nevus underwent full imaging examination including fundus photography, fluorescein angiography, indocyanine green angiography, spectral domain OCT, and OCT-A. The OCT-A features were analyzed and correlated with conventional angiography findings and spectral domain OCT. RESULTS: There were 11 eyes from 11 patients (6 men and 5 women, mean age of 65 ± 20.4 years) included in the analysis. Fluorescein angiography and indocyanine green angiography disclosed CNV in 90% and 83%, respectively. Optical coherence tomography angiography displayed CNV network in 11 eyes (100%) and the pattern was classified as "sea-fan" in 8 (73%) and "long filamentous linear vessels" in 3 (27%) eyes. Distinct from CNV, intrinsic vasculature within the nevus was observed in six eyes (55%), corresponding to those with chronic retinal pigment epithelium changes. CONCLUSION: Optical coherence tomography angiography is a useful imaging technique to disclose CNV associated with choroidal nevus. Despite the presence of intraretinal or subretinal fluid and hemorrhage, OCT-A revealed the CNV in all cases, results noninferior to indocyanine green angiography. This imaging modality can be useful for analysis of long-standing nevi with related exudation.
Optical coherence tomography angiography features of choroidal neovascularization associated with choroidal nevus / M. Pellegrini, F. Corvi, E.A.T. Say, C.L. Shields, G. Staurenghi. - In: RETINA. - ISSN 0275-004X. - 38:7(2018), pp. 1338-1346.
|Titolo:||Optical coherence tomography angiography features of choroidal neovascularization associated with choroidal nevus|
|Settore Scientifico Disciplinare:||Settore MED/30 - Malattie Apparato Visivo|
|Data di pubblicazione:||2018|
|Data ahead of print / Data di stampa:||29-mag-2017|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1097/IAE.0000000000001730|
|Appare nelle tipologie:||01 - Articolo su periodico|
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