Recent studies have demonstrated that in mice, the estrogen receptor alpha (ERÎ±) is expressed in the liver and has a direct effect on the regulation of the hepatic genes relevant for energy metabolism and drug metabolism. The sex-related differential expression of the hepatic ERÎ± raises the questions as to whether this receptor is responsible for the sexual differences observed in the physiopathology of the liver.
|Titolo:||Sexual dimorphism and estrogen action in mouse liver|
|Parole Chiave:||Energy metabolism; Female mammals; Fertility; Liver; Sex differences; Sex-related diseases; Sexual differentiation; Biochemistry, Genetics and Molecular Biology (all)|
|Settore Scientifico Disciplinare:||Settore BIO/14 - Farmacologia|
|Data di pubblicazione:||10-dic-2017|
|Digital Object Identifier (DOI):||10.1007/978-3-319-70178-3_8|
|Tipologia:||Book Part (author)|
|Appare nelle tipologie:||03 - Contributo in volume|