Scientific Opinion on the safety and efficacy of Kemzyme((R)) Plus Dry (endo-1,3(4)-beta-glucanase, endo-1,4-beta-glucanase, alpha-amylase, bacillolysin and endo-1,4-beta-xylanase) for poultry, ornamental birds and piglets (weaned) : EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)

Kemzyme (R) Plus Dry is a preparation of four glycosyl hydrolases and a protease which is to be used as a feed additive for poultry, ornamental birds and weaned piglets. Based on the tolerance studies provided, the Panel considered that the additive is safe for chickens and turkeys for fattening and laying hens at the maximum dose of 1 000 mg additive/kg feed and in weaned piglets at a maximum dose of 500 mg additive/kg feed. The conclusion can be extended/extrapolated to avian species at the same dose. The Panel concluded that the additive is safe for consumers. The additive is not irritant to skin or eyes but should be regarded as a potential skin sensitiser and as hazardous by inhalation. No risks to the environment are expected and no further environmental risk assessment is required. Owing to the lack of data, the efficacious dose in units of enzyme activity could not be established. The FEEDAP Panel concluded that the additive has the potential to be efficacious at a nominal dose of 500 mg additive/kg feed in chickens for fattening and laying hens and at a nominal dose of 250 mg additive/kg feed in turkeys for fattening. These conclusions can be extended to chickens reared for laying and turkeys reared for breeding at the corresponding dose. The conclusions on efficacy in poultry species can be extrapolated to minor poultry species and ornamental birds at the nominal dose of 250 mg/kg feed for fattening birds and of 500 mg/kg feed for laying birds. The FEEDAP Panel could not conclude on the efficacy in weaned piglets.