The present invention relates to a method for the production of tenocytes, highly specialized cells that form tendons connective tissues, starting from mammalian mesenchymal stem cells. Moreover, the invention relates to a method for the characterization of tenocytes and mammalian mesenchymal stem cells. It is known that tendon damages can seriously and permanently impair the mobility and functionality of an articulation. This kind of lesions frequently occurs in athletes or race animals that subject their tendons to heavy and sustained efforts due to their physical activity. It is known that race horses suffer from damages to limb tendons and that this kind of accident can lead, as an extreme consequence, to put the animals down. The invention describes an innovative therapeutic method for such tendons damages.
New method for in vitro production of tenocytes / F. Cremonesi, P. Mariani, S. Violini.
|Titolo:||New method for in vitro production of tenocytes|
CREMONESI, FAUSTO (Primo)
|Enti collegati:||Università degli Studi di Milano|
Fonadazione Parco Tecnologico Lodi
|Codice di pubblicazione:||WO2010/007542|
|Data di pubblicazione:||21-gen-2010|
|Parole Chiave:||Mesenchymal stem cells ; tenocytes in vitro derivation ; tendon injuries ; horse|
|Settore Scientifico Disciplinare:||Settore VET/10 - Clinica Ostetrica e Ginecologia Veterinaria|
|Citazione:||New method for in vitro production of tenocytes / F. Cremonesi, P. Mariani, S. Violini.|
|Numero di deposito:||PCT/IB2009/052542|
|Appare nelle tipologie:||09 - Brevetto, privativa o norma|