Background. Early and late complications related to the pancreas after simultaneous kidney-pancreas transplantation (SKPT) frequently result in graft loss. The authors describe a surgical rescue technique that allows salvage of the pancreatic graft when surgical complications appear after the transplant. Methods. Of 158 patients who underwent SKPT, 7 were identified with posttransplant complications that required surgical salvage of the pancreas allograft. The surgical salvage technique consisted of the following: pancreatoduodenectomy with conversion from whole-pancreas transplant with bladder or enteric diversion to segmental graft with duct injection (three cases) and conversion from whole-pancreas transplant with duct injection (four cases). Results. Five of seven pancreas allografts are still functioning, with a mean follow-up of 28 months (range, 6-42 months). Conclusion. The described surgical treatment may be useful for surgical salvage of the pancreatic allograft, without major impairment of endocrine function.
Successful surgical salvage of pancreas allograft / E. Orsenigo, M. Cristallo, C. Socci, R. Castoldi, P. Fiorina, L. Invernizzi, R. Caldara, A. Secchi, V. Di Carlo. - In: TRANSPLANTATION. - ISSN 0041-1337. - 75:2(2003), pp. 233-236.
Successful surgical salvage of pancreas allograft
P. Fiorina;A. Secchi;V. Di Carlo
2003
Abstract
Background. Early and late complications related to the pancreas after simultaneous kidney-pancreas transplantation (SKPT) frequently result in graft loss. The authors describe a surgical rescue technique that allows salvage of the pancreatic graft when surgical complications appear after the transplant. Methods. Of 158 patients who underwent SKPT, 7 were identified with posttransplant complications that required surgical salvage of the pancreas allograft. The surgical salvage technique consisted of the following: pancreatoduodenectomy with conversion from whole-pancreas transplant with bladder or enteric diversion to segmental graft with duct injection (three cases) and conversion from whole-pancreas transplant with duct injection (four cases). Results. Five of seven pancreas allografts are still functioning, with a mean follow-up of 28 months (range, 6-42 months). Conclusion. The described surgical treatment may be useful for surgical salvage of the pancreatic allograft, without major impairment of endocrine function.Pubblicazioni consigliate
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