Herein we report the outcomes of pediatric kidney recipients who underwent transplantation at least 10 years prior. A cohort of 36 patients (mean age, 26.4 +/- 6 years) with a mean follow-up time of 14.2 +/- 4 years was selected for the study. Immunosuppression consisted of cyclosporine and steroids. Actuarial patient and graft survivals 15 years after the transplantation were 97% and 86%, respectively. Only 1 patient died due to a complicated sclerosant peritonitis. Graft function was good with a mean serum creatinine of this selected cohort of 1.5 +/- 0.6 mg/dL. Eighteen percent were class 1, 33% class 2, and 49% chronic kidney disease. Hypertension was treated in almost 80% of the patients. The majority of patients were smaller than the average population with a final height (between 0 and -2) standard deviation score (HSDS) but only 27% had a severe growth impairment (HSDS >-2). Regarding nutritional status, fewer than 30% were overweight and only 1 patient was obese with a body mass index (BMI) > 30. The majority of patients, except 2 mentally retarded individuals, are or have been attending normal school and achieved full-time employment. In conclusion, long-term survivors of a kidney transplant received during childhood reached a high degree of rehabilitation despite a long period of immunosuppression.
Pediatric kidney transplantation : a snapshot 10 years later / M. Ferraresso, L. Ghio, M. Raiteri, M. Belinghieri, C. Beretta, V. Martina, A. Edefonti, L. Berardinelli. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - 40:6(2008), pp. 1852-1853.
|Titolo:||Pediatric kidney transplantation : a snapshot 10 years later|
FERRARESSO, MARIANO (Primo)
BERARDINELLI, LUISA (Ultimo)
|Parole Chiave:||renal-transplantation; children|
|Settore Scientifico Disciplinare:||Settore MED/18 - Chirurgia Generale|
|Data di pubblicazione:||2008|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.transproceed.2008.05.003|
|Appare nelle tipologie:||01 - Articolo su periodico|