Reverse or inverted dipping (ie, the phenomenon characterized by higher nighttime compared with daytime blood pressure values) is an alteration of circadian blood pressure rhythm frequently documented in hypertension, type 2 diabetes mellitus, chronic kidney disease, and sleep apnea syndrome, and generally regarded as a harmful condition. Available literature on the clinical and prognostic implications of reverse dipping is scanty. The present article will review a number of relevant issues concerning reverse dipping, in particular: (1) its possible mechanisms; (2) prevalence and clinical correlates, (3) concomitant cardiac and extracardiac subclinical organ damage; (4) association with acute and chronic cardiovascular diseases; (5) prognostic value in predicting cardiovascular events and mortality; and (6) therapeutic interventions aimed at reverting this abnormal circadian blood pressure rhythm.

Clinical and prognostic significance of a reverse dipping pattern on ambulatory monitoring : an updated review / C. Cuspidi, C. Sala, M. Tadic, E. Gherbesi, A. De Giorgi, G. Grassi, G. Mancia. - In: THE JOURNAL OF CLINICAL HYPERTENSION. - ISSN 1524-6175. - 19:7(2017), pp. 713-721. [10.1111/jch.13023]

Clinical and prognostic significance of a reverse dipping pattern on ambulatory monitoring : an updated review

C. Sala
Secondo
;
E. Gherbesi;
2017

Abstract

Reverse or inverted dipping (ie, the phenomenon characterized by higher nighttime compared with daytime blood pressure values) is an alteration of circadian blood pressure rhythm frequently documented in hypertension, type 2 diabetes mellitus, chronic kidney disease, and sleep apnea syndrome, and generally regarded as a harmful condition. Available literature on the clinical and prognostic implications of reverse dipping is scanty. The present article will review a number of relevant issues concerning reverse dipping, in particular: (1) its possible mechanisms; (2) prevalence and clinical correlates, (3) concomitant cardiac and extracardiac subclinical organ damage; (4) association with acute and chronic cardiovascular diseases; (5) prognostic value in predicting cardiovascular events and mortality; and (6) therapeutic interventions aimed at reverting this abnormal circadian blood pressure rhythm.
cardiovascular disease; cardiovascular prognosis; hypertension; reverse dipping; target organ damage; treatment; adolescent; adult; aged; blood pressure; blood pressure monitoring, ambulatory; cardiovascular diseases; circadian rhythm; diabetes mellitus, type 2; female; humans; hypertension; male; middle aged; prevalence; prognosis; renal insufficiency, chronic; sleep; sleep apnea syndromes; young adult; internal medicine; endocrinology, diabetes and metabolism; cardiology and cardiovascular medicine
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
2017
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/554044
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