Background: Neuroendocrine carcinoma is an uncommon histology for breast cancer. Case Report: Our patient underwent right quadrantectomy for a neuroendocrine carcinoma in 1984 and had a bone relapse 30 years later. After thorough pathological and immunohistochemical analysis the diagnosis was confirmed and HER2 amplification was observed. Here we discuss the management, rationale and results of HER2-targeted therapy in advanced neuroendocrine breast carcinoma.
HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature / A. Gevorgyan, G. Bregni, G. Galli, E. Zanardi, F. De Braud, S. Di Cosimo. - In: BREAST CARE. - ISSN 1661-3791. - 11:6(2016 Dec), pp. 424-426. [10.1159/000453572]
HER2-Positive Neuroendocrine Breast Cancer: Case Report and Review of Literature
A. GevorgyanPrimo
;G. Galli;F. De Braud;
2016
Abstract
Background: Neuroendocrine carcinoma is an uncommon histology for breast cancer. Case Report: Our patient underwent right quadrantectomy for a neuroendocrine carcinoma in 1984 and had a bone relapse 30 years later. After thorough pathological and immunohistochemical analysis the diagnosis was confirmed and HER2 amplification was observed. Here we discuss the management, rationale and results of HER2-targeted therapy in advanced neuroendocrine breast carcinoma.
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