ObjectivesTo investigate the quality of sleep and the psychological profiles of a large cohort of Italian patients with burning mouth syndrome (BMS) and to clarify the relationships between these variables and pain. MethodsIn this case-control study, 200 patients with BMS vs an equal number of age- and sex-matched healthy controls, recruited in 10 universities, were enrolled. The Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Hamilton Rating Scale for Depression (HAM-D), Hamilton Rating Scale for Anxiety (HAM-A), Numeric Pain Intensity Scale (NRS) and Total Pain Rating Index (T-PRI) were administered. Descriptive statistics, including the Mann-Whitney U test and hierarchical multiple linear regression analysis, were used. ResultsPoor sleep quality (PSQI5) was present in 78.8% (160) patients with BMS. BMS patients had statistically higher scores in all items of the PSQI and ESS than the healthy controls (p<.001). A depressed mood and anxiety correlated positively with sleep disturbance. The Pearson correlations were 0.570 for the PSQI vs HAM-D (p<.001) and 0.549 for the PSQI vs HAM-A (p<.001). Pain intensity (NRS) poorly correlated to sleep quality; the Pearson correlation was 0.162 for the PSQI vs NRS (p=.021). ConclusionsThe BMS patients showed a poor sleep quality, anxiety and depression, as compared with the controls, highlighting the relationships between oral burning, sleep and mood.

The association between Burning Mouth Syndrome and Sleep Disturbance: a case-control multicentre study / D. Adamo, A. Sardella, E. Varoni, C. Lajolo, M. Biasotto, G. Ottaviani, P. Vescovi, T. Simonazzi, M. Pentenero, M. Ardore, F. Spadari, G. Bombeccari, L. Montebugnoli, D.B. Gissi, G. Campisi, V. Panzarella, M. Carbone, L. Valpreda, M. Giuliani, M. Aria, L. Lo Muzio, M.D. Mignogna. - In: ORAL DISEASES. - ISSN 1354-523X. - 24:4(2018 May), pp. 638-649. [10.1111/odi.12807]

The association between Burning Mouth Syndrome and Sleep Disturbance: a case-control multicentre study

A. Sardella;E. Varoni;F. Spadari;G. Bombeccari;
2018-05

Abstract

ObjectivesTo investigate the quality of sleep and the psychological profiles of a large cohort of Italian patients with burning mouth syndrome (BMS) and to clarify the relationships between these variables and pain. MethodsIn this case-control study, 200 patients with BMS vs an equal number of age- and sex-matched healthy controls, recruited in 10 universities, were enrolled. The Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Hamilton Rating Scale for Depression (HAM-D), Hamilton Rating Scale for Anxiety (HAM-A), Numeric Pain Intensity Scale (NRS) and Total Pain Rating Index (T-PRI) were administered. Descriptive statistics, including the Mann-Whitney U test and hierarchical multiple linear regression analysis, were used. ResultsPoor sleep quality (PSQI5) was present in 78.8% (160) patients with BMS. BMS patients had statistically higher scores in all items of the PSQI and ESS than the healthy controls (p<.001). A depressed mood and anxiety correlated positively with sleep disturbance. The Pearson correlations were 0.570 for the PSQI vs HAM-D (p<.001) and 0.549 for the PSQI vs HAM-A (p<.001). Pain intensity (NRS) poorly correlated to sleep quality; the Pearson correlation was 0.162 for the PSQI vs NRS (p=.021). ConclusionsThe BMS patients showed a poor sleep quality, anxiety and depression, as compared with the controls, highlighting the relationships between oral burning, sleep and mood.
anxiety; burning; insomnia symptoms; mood disorders; pain; sleep
Settore MED/28 - Malattie Odontostomatologiche
20-nov-2017
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/551519
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