Serum C1 esterase inhibitor was determined in 138 members of 18 italian families with hereditary angioedema by immunochemical and enzymatic assays. On the basis of quantitative and functional findings, the type A of hereditary angioedema was diagnosed in 44 subjects, and the type B in 15. Some technical devices concerning serum sample handling were identified. The influence of heparin, EDTA, and citrate on C1 esterase inhibitor activity of normal plasma was also investigated.
Studio mediante dosaggio enzimatico e immunochemico dell'inibitore della C1 esterasi in 59 pazienti affetti da angioedema ereditario / A. Agostoni, B. Marasini, M. Cicardi, G. Martignoni, O. Brenna. - In: BOLLETTINO DELL'ISTITUTO SIEROTERAPICO MILANESE. - ISSN 0021-2547. - 56:1(1977), pp. 22-28.
Studio mediante dosaggio enzimatico e immunochemico dell'inibitore della C1 esterasi in 59 pazienti affetti da angioedema ereditario
B. MarasiniWriting – Review & Editing
;M. CicardiInvestigation
;O. BrennaWriting – Original Draft Preparation
1977
Abstract
Serum C1 esterase inhibitor was determined in 138 members of 18 italian families with hereditary angioedema by immunochemical and enzymatic assays. On the basis of quantitative and functional findings, the type A of hereditary angioedema was diagnosed in 44 subjects, and the type B in 15. Some technical devices concerning serum sample handling were identified. The influence of heparin, EDTA, and citrate on C1 esterase inhibitor activity of normal plasma was also investigated.
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