Some studies have suggested that tobacco smoking may affect the risk of endometriosis, but published data are controversial. We conducted a case control study on the association between smoking and endometriosis risk Cases of endometriosis included 90 women (median age 35, range 19-49) with incident, i.e. laparoscopically diagnosed within the year before interview, histologically confirmed endometriosis. Controls were 90 women (median age 35.5, range 17- 76) admitted for a wide spectrum of acute conditions unrelated to known potential risk factors for endometriosis. Compared with never smokers the OR of endometriosis was 2.36 (95% CI 1.04-5.35) in ever smokers. These findings were largely consistent in strata of age and education. Considering separately nulliparous and parous women the estimated OR of endometriosis in ever smokers were 1.51 (95%CI 0.26-11.36) and 2.52. In conclusion despite the limitations of this study the present analysis suggest that smoking may increase the risk of endometriosis in nulliparae women attending an infertility clinic: this finding may at least in part due to the effect of smoking on infertility.

Smoking habits and endometriosis risk among infertile women : results from a case control study / E. Garavaglia, E. Ricci, R. Cioffi, G. Trojano, A. Bulfoni, F. Parazzini, P. Viganò. - In: ITALIAN JOURNAL OF GYNAECOLOGY & OBSTETRICS. - ISSN 2385-0868. - 29:3(2017 Sep), pp. 15-18. [10.14660/2385-0868-72]

Smoking habits and endometriosis risk among infertile women : results from a case control study

F. Parazzini
Penultimo
;
2017

Abstract

Some studies have suggested that tobacco smoking may affect the risk of endometriosis, but published data are controversial. We conducted a case control study on the association between smoking and endometriosis risk Cases of endometriosis included 90 women (median age 35, range 19-49) with incident, i.e. laparoscopically diagnosed within the year before interview, histologically confirmed endometriosis. Controls were 90 women (median age 35.5, range 17- 76) admitted for a wide spectrum of acute conditions unrelated to known potential risk factors for endometriosis. Compared with never smokers the OR of endometriosis was 2.36 (95% CI 1.04-5.35) in ever smokers. These findings were largely consistent in strata of age and education. Considering separately nulliparous and parous women the estimated OR of endometriosis in ever smokers were 1.51 (95%CI 0.26-11.36) and 2.52. In conclusion despite the limitations of this study the present analysis suggest that smoking may increase the risk of endometriosis in nulliparae women attending an infertility clinic: this finding may at least in part due to the effect of smoking on infertility.
risk factor smoking endometriosis;
Settore MED/40 - Ginecologia e Ostetricia
set-2017
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/550319
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